Amblyopia
Conditions
Interventions
Control:Best optical correction with standard patch
Sponsors
The First Affiliated Hospital of Nanjing Medical University
Eligibility
Sex/Gender
All
Age
4 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1. Patients from 4 to 12 years old (including 4 and 12 years old), regardless of gender; 2. According to the expert consensus on amblyopia diagnosis (2011) 1 of strabismus and pediatric ophthalmology group of Ophthalmology branch of Chinese Medical Association, the patients were diagnosed as amblyopia, that is, the best corrected vision of monocular or binocular caused by monocular strabismus, uncorrected anisometropia, high ametropia and form deprivation during visual development was lower than that of corresponding age, or the difference of binocular vision was 2 lines or more. The lower limit of normal visual acuity for children of different ages: the lower limit of normal visual acuity for children aged 4 to 5 years is 0.5, and the lower limit of normal visual acuity for children aged 6 and above is 0.7. 3. The guardian of the subject can understand the purpose of the test and is willing to sign the informed consent. 4. Subjects who can cooperate with treatment and related ophthalmic examination.
Exclusion criteria
Exclusion criteria: 1. Subjects with tumor, heart disease (blood pressure > 110 / 70 mmHg in 4-6 years old children, blood pressure > 120 / 80 mmHg in 7-12 years old children), hypertension and epilepsy; 2. Subjects with implanted electronic devices, such as pacemakers, etc.; 3. Subjects who had mental illness; 4. Any subject who suffers from photophobia and tears due to keratitis, conjunctivitis, and entropion; 5. Subjects with vertigo or acrophobia; 6. Subjects with congenital glaucoma, congenital ptosis, dacryocystitis, trauma and other organic diseases; 7. Subjects who have received the treatment of amblyopia by covering therapy or treatment instrument within 4 weeks before enrollment will not be included in the treatment of wearing corrective glasses and mydriasis; 8. Subjects who participated in other clinical trials 4 weeks before enrollment; 9. For safety reasons or the interests of patients, the clinician believes that other circumstances that should not participate in this trial, such as the subjects with serious heart, liver and kidney diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effectiveness of amblyopia treatment with VR; | — |
Secondary
| Measure | Time frame |
|---|---|
| Effectiveness of amblyopia treatment with VR;Effectiveness of amblyopia treatment with VR;Stereopsis: distance and near, respectively;Contrast sensitivity function (CSF); | — |
Countries
China
Contacts
Public ContactLiu Hu
The First Affiliated Hospital of Nanjing Medical University
Outcome results
None listed