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Clinical study for stem cells in the treatment of severe novel coronavirus pneumonia (COVID-19)

Clinical study for stem cells in the treatment of severe novel coronavirus pneumonia (COVID-19)

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000031494
Enrollment
Unknown
Registered
2020-04-02
Start date
2020-02-01
Completion date
Unknown
Last updated
2020-04-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Corona Virus Disease 2019

Interventions

Experimental group:Conventional medication + Infusion of mesenchymal stem cells

Sponsors

Huangshi Hospital of Traditional Chinese Medicine (Municipal Infectious Disease Hospital)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: (1) Aged 18 to 90 years old, male or female; (2) Patients with a definite diagnosis of new type of coronavirus pneumonia; (3) Expected survival time > 10 days; (4) Serology: HIV antibody negative; hepatitis B surface antigen, e antigen negative; hepatitis C antibody negative; female patients with negative pregnancy test; ALT, AST <=2.5 ULN; for patients with liver metastases, ALT, AST <=5 ULN; ALP <=2.5 ULN; serum urea nitrogen and creatinine <=1.5 ULN; serum total bilirubin <1.5 times the upper limit of normal; (6) Patients or their legal representatives can understand and voluntarily sign informed consent.

Exclusion criteria

Exclusion criteria: 1. With any autoimmune disease; 2. with malignant tumors; 3. Participated in other clinical studies within three months before entering the group; 4. Severe allergic history, allergic to T cell therapy products or other biological agents; 5. Pregnant, planning to become pregnant or lactating women; 6. Patients with severe systemic diseases who are not suitable for entering the study, including but not limited to severe liver dysfunction, severe coagulation disorders, severe mental diseases, etc.; 7. Previously received other stem cell therapy, had received CIK cell therapy within two months; 8. Researchers believe that other conditions should not be included in this trial.

Design outcomes

Primary

MeasureTime frame
Chest Imaging;lung function;ADL;

Countries

China

Contacts

Public ContactFeng Ganzhu

Huangshi Hospital of Traditional Chinese Medicine

zhu1635253@163.com+86 18951762691

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 17, 2026