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Repetitive Transcranial Magnetic Stimulation over dorsolateral DLPFC in methamphetamine dependence

Unilateral and bilateral repetitive transcranial magnetic stimulation (r-TMS) over dorsolateral prefrontal cortex (DLPFC) for methamphetamine addiction: a randomized multi-center double-blinded clinical trial

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000031470
Enrollment
Unknown
Registered
2020-04-02
Start date
2020-04-06
Completion date
Unknown
Last updated
2020-04-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Addiction

Interventions

Group 1:10Hz rTMS over left DLPFC for 10 mins daily, 5 days a week, 4 weeks, 20 treatment in total
Group 2:1Hz rTMS over right DLPFC for 10 mins, then 10Hz rTMS over left DLPFC for 10 mins daily, 5 days a week, 4 weeks, 20 treatment in total
Group 3:10Hz rTMS over Vertex for 10 mins daily, 5 days a week, 4 weeks, 20 treatment in total

Sponsors

Shanghai Mental Health Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: (1) Meet DSM-5 criteria for substance abuse; (2) Aged 18-60 years; (3) Junior high school degree or above; (4) Consent to attend this study; (5) The drug abuse time is more than one year, the frequency of use is greater than one week, and the monthly use is greater than 1 gram.

Exclusion criteria

Exclusion criteria: (1) Have contraindications to TMS (head trauma, epilepsy or the history of epilepsy, metal implant etc.); (2) Psychiatric illnesses; (3) Physical ailments; (4) Intellectual impairment (IQ<90); (5) Received medication treatment recently; (6) Received psychoterapy or TMS intervation on the last 6 months.

Design outcomes

Primary

MeasureTime frame
clinical outcomes;craving;qEEG;relapse;Cognitive measures;neuropsychological measures;

Countries

China

Contacts

Public ContactTi-fei Yuan

Shanghai Mental Health Center

ytf0707@126.com18614086633

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026