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The effect of Intravenous dexmedetomidine on epidural analgesia for labor and epidural anesthesia for cesarean section

The effect of Intravenous dexmedetomidine on epidural analgesia for labor and epidural anesthesia for cesarean section

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000031469
Enrollment
Unknown
Registered
2020-04-02
Start date
2020-04-01
Completion date
Unknown
Last updated
2020-04-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Labor analgesia \ cesarean section

Interventions

experimental group:Dexmedetomidine
control group:Normal saline

Sponsors

Tianjin Central obstetrics and Gynecology Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 35 Years

Inclusion criteria

Inclusion criteria: 1. ASA class I-II, 20-35-year-old primipara, 38-41 weeks of gestation; 2. The primipara who transferred to caesarean section midway through epidural labor analgesia; 3. Patients without previous abdominal and perineal operation history; 4. Patients with epidural labor analgesia.

Exclusion criteria

Exclusion criteria: 1. Patients who can't perform epidural block in emergency cesarean section; 2. Patients with Epidural Delivery Analgesia catheter prolapse; 3. Patients with gestational hypertension, heart disease, morbid obesity and diabetes (including gestational diabetes); 4. Patients who are allergic to local anesthetics and opioids; 5. Patients with pain relief time more than 24 hours.

Design outcomes

Primary

MeasureTime frame
Failure rate of epidural anesthesia;

Secondary

MeasureTime frame
Ramsay Sedation score;Catecholamine concentration;The visual analog scales;

Countries

China

Contacts

Public ContactPeijun Zhang

Tianjin Central Obstetrics and Gynecology Hospital

zhangpeijun163@126.com+86 15122119658

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026