Hepatic insufficiency
Conditions
Interventions
Test group:Basic liver protection therapy + Babaodan capsule
control group:Basic liver protection therapy
Sponsors
Shanghai Public Health Clinical Center
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. The patient receive hepatectomy and met the following conditions: (1) Aged 18-70 years old; (2) On the first day after operation, the child Pugh score of liver function was grade A or B; (3) More than one segment of liver was resected. 2. If the patient has malignant tumor, R0 resection is needed; 3. Patients without infection and no record of using antibiotics before operation; 4. Patients who can drink water and take medicine from the first day after operation.
Exclusion criteria
Exclusion criteria: 1. Patients who are allergic to babaodan and its similar drugs or have obvious gastrointestinal reactions after taking the medicine; 2. The child Pugh score of liver function was grade C on the first day after operation; 3. Patients who had a history of esophageal variceal bleeding before operation; 4. Patients with severe hypertension, diabetes, kidney disease, heart failure and other basic diseases; 5. Pregnant women; 6. Patients with infection of biliary system, abdominal cavity, lung, urinary system, etc. who need antibiotics before operation; 7. Patients with active immune liver disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| total bilirubin;albumin;PT;ascites;hepatic encephalopathy; | — |
Secondary
| Measure | Time frame |
|---|---|
| ALT;AST; | — |
Countries
China
Contacts
Public ContactLi Yesheng
Shanghai Public Health Clinical Center
Outcome results
None listed