Novel Coronavirus Pneumonia (COVID-19)
Conditions
Interventions
Experimental group:Conventional treatment regimen + MSC treatment
Control group:Conventional treatment regimen
Sponsors
The Fifth Medical Center of PLA General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Male or female patients aged form 18 to 80 years; 2) Willing to sign informed consent; 3) Confirmed cases who meet "Novel Coronavirus Pneumonia Diagnosis and Treatment Protocol" revised by the National Health Commission of the Peoples Republic of China. 4) High-resolution CT indicates interstitial injures in the lungs (honeycomb shadows or grid shadows).
Exclusion criteria
Exclusion criteria: 1) Pregnant or lactating women; 2) High-resolution CT before the onset of the disease suggests the presence of interstitial injures in lungs; 3) Acute interstitial lung injures caused by other reasons (within two weeks); 4) Invasive ventilator assisted ventilation; 5) Multiple organ dysfunction syndrome.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Electrocardiogram;St George's Respiratory Questionnaire Score;High resolution CT for chest;Blood gas analysis;Percutaneous blood oxygen saturation;6 min walking distance;Pulmonary function VCmax;Blood routine;Liver and kidney function;Cytokine analysis;Immunoglobulin;Lymphocyte subsets;Coagulation;Myocardial enzymes;Serum ferritin;Procalcitonin;IL-6;Lactic acid;D-Dimer;CRP; | — |
Countries
China
Contacts
Public ContactFu-Sheng Wang
The Fifth Medical Center of PLA General Hospital
Outcome results
None listed