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Clinical application of multimodal combination in pressure injury of patients

Clinical application of multimodal combination in pressure injury of patients: a non-randomised controllred trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000031416
Enrollment
Unknown
Registered
2020-03-31
Start date
2020-04-15
Completion date
Unknown
Last updated
2020-04-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pressure injury

Interventions

PRP group:Traditional wound care and PRP therapy
HBOT group:Traditional wound care and HBOT
Combined VAC group:PRP, VAC and Traditional wound care
Combined HBOT group:PRP, HBO and Traditional wound care
Control group:Traditional wound care

Sponsors

West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. According to the Braden scale and the classification criteria of PI in the guidelines for the prevention and treatment of pressure sore developed by the American pressure sore Advisory Council (NPUAP), the European pressure sore Advisory Council (EPUAP) and the Pan Pacific pressure injury Alliance (pppia), patients who meet the pressure sore conditions and are 3 or 4 or non staged pressure sore; 2. Patients with limited activities of daily life (ADL <= 60 points); 3. Patients over 20 years old; 4. Braden score <= 12 points.

Exclusion criteria

Exclusion criteria: 1. Patients with ulcer caused by malignant tumor; 2. Patients with blood diseases; 3. Patients with untreated pneumothorax (tension pneumothorax), mediastinal emphysema, pulmonary cavity and history of oxygen poisoning; 4. Patients with gangrene; 5. Patients with severe cognitive impairment who can not cooperate with the treatment.

Design outcomes

Primary

MeasureTime frame
Bates-Jensen scale;Pressure Ulcer Scale for Healing;

Secondary

MeasureTime frame
Blood routine;Biochemical results;CRP;CS;CS;

Countries

China

Contacts

Public ContactHongying Jiang

West China Hospital of Sichuan University

b.julia7755@163.com+86 18980606073

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026