Intestinal dyabacteriosis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients who voluntarily sign informed consent; 2. Men and women over 18 years old; 3. Outpatients who need to have a colonoscopy.
Exclusion criteria
Exclusion criteria: 1. Patients with systemic or local malignant tumors or patients who cannot stop immunosuppressive drugs; 2. patients with chronic diarrhea, inflammatory bowel disease, infectious gastrointestinal disease, functional constipation, and partial intestinal polyps (a. Size >= 2cm,b number of polyps > 3, and c need EMR treatment, if any one or more of them are met, they will be excluded); 3. Abnormal stool routine results: fecal occult blood (+) or leukocyte (+); When fecal occult blood (+), but colonoscopy results are normal, can be included in this study; 4. Patients with severe mental illness; 5. Those who have a history of drug abuse or alcohol abuse or need to drink a lot in the past 1 month; 6. Patients with drug allergy in this study; 7. Those who can't stop using the drugs or health products / foods that cause diarrhea and affect the intestinal flora in the test include western drugs or proprietary Chinese drugs, antibiotics, probiotic drug preparations, probiotic health products / foods, probiotic yoghurt, etc; 8. Those who have had colonoscopy (or intestinal cleansing treatment) in the past 1 month; 9. Pregnant or lactating women; 10. Those who are participating in or completing other clinical trials less than 3 months later; 11. Those who the researchers don't think are suitable for selection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| High throughput sequencing of feces;incidence of diarrhea; | — |
Secondary
| Measure | Time frame |
|---|---|
| gastrointestinal adverse reaction; | — |
Countries
China
Contacts
Suzhou Ninth People's Hospital