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Decalcification with fibrosa layer stripping technique for minimally invasively aortic valve replacement in patients with severe calcified aortic valve stenosis

Decalcification with fibrosa layer stripping technique for minimally invasively aortic valve replacement in patients with severe calcified aortic valve stenosis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000031338
Enrollment
Unknown
Registered
2020-03-28
Start date
2016-02-15
Completion date
Unknown
Last updated
2020-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aortic valve stenosis

Interventions

Experimental group:Fibrosa layer stripping technique
Conventional:Conventional decalcification

Sponsors

Beijing Anzhen Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
63 Years to 84 Years

Inclusion criteria

Inclusion criteria: Adult patients (>=18 years) with severe calcific aortic valve stenosis admitted to Beijing Anzhen Hospital were eligible for inclusion in our study. Diagnosis of calcific AS was established using an echocardiographic examination. Severe calcific aortic valve stenosis was assessed by echocardiography with findings of a maximum aortic jet velocity >4.0 m/s, mean transvalvular gradient >40 mm Hg, or continuity equation valve area <1.0 cm2 or valve area indexed for body surface area <0.6 cm2/m2

Exclusion criteria

Exclusion criteria: Planned concomitant procedures, history of cardia surgery, deformity of thoraxporcelain ascend aorta, high surgical risk according to the criteria of the STS-PROM.

Design outcomes

Primary

MeasureTime frame
Indexed effective orifice area;Mean Transvalvular Gradient;—

Secondary

MeasureTime frame
Cross-clamp Time;Cardiopulmonary Bypass Time;Operative Time;Mechanical Ventilation Time;Length of Intensive Care Unit stay;Length of hospital stay;major bleeding events;Cardiac Tamponade;Degree of paravalvular regurgitation;Packed red blood cells transfusion;Reoperation;Sternal wound infection;Myocardial infarction;Cerebro-vascular accident;Stroke;New pacemaker;Permanent pacemaker implantation;Endocarditis;Respiratory failure;Prosthesis-related early mortality;All-cause mortality;—

Countries

China

Contacts

Public ContactXiubin Yang

Beijing Anzhen Hospital, Capital Medical University

xiubinyang@yahoo.com+86 10 64456896

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026