Lumbar degenerative diseases
Conditions
Interventions
Sarcopenia :None
Control group:None
Sponsors
Shanghai Tenth People's Hospital
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged >= 65 years; 2. Patients with intermittent claudication or lumbago accompanied by lower extremity pain and numbness; 3. The type of imaging manifestation is round and oval spinal stenosis, which can be achieved by bilateral decompression through unilateral approach; 4. Patients with single segment lumbar spinal stenosis and lumbar instability (lumbar instability refers to the lateral slide of lumbar dynamic film more than 3 mm or the angle of upper and lower vertebral endplate greater than 11 degree); 5. Patients with lumbar degenerative or isthmic spondylolisthesis (within meyerding index I) who need surgical treatment; 6. Patients whose symptoms last for 6 months, and whose normal conservative treatment is ineffective, seriously affect their lives.
Exclusion criteria
Exclusion criteria: 1. Patients with severe bilateral spinal stenosis (also known as trilobal stenosis) accompanied by symptoms of both lower limbs and patients whose preoperative evaluation indicated that unilateral approach was difficult to achieve decompression of contralateral recess or intervertebral foramen; 2. Patients with spinal surgery, lumbar fracture, active infection and spinal tumor; 3. Patients with coronal or sagittal malformations requiring surgical treatment; 4. Meyerding grade II or above slip; 5. Patients who are not suitable for surgery due to any internal medicine, mental and psychological diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Operation time;Intraoperative blood loss;Radiation exposure;Length of hospital stay;Complications;VAS score for back pain and leg pain (preoperatively, and postoperatively at 3, 6, 12 months and last follow up);JOA score (preoperatively, and postoperatively at 12 months and last follow up);ODI score (preoperatively, and postoperatively at 12 months and last follow up);Fusion rate (at last follow up).;Skeletal muscle mass;Handgrip strength; | — |
Secondary
| Measure | Time frame |
|---|---|
| Gender;Age;Body mass index;Bone mineral density;Disease course;Distribution of treated segment;Psoas muscle index; | — |
Countries
China
Contacts
Public ContactGuangfei Gu
Spine Surgery, Shanghai Tenth People's Hospital
Outcome results
None listed