Relationship between aneurysm wall enhancement and rupture rate in patients with unruptured intracranial aneurysms: a high-resolution vessel wall magnetic resonance imaging (VW-MRI) study

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2000031263

Enrollment

Unknown

Registered

2020-03-26

Start date

2020-03-18

Completion date

Unknown

Last updated

2020-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intracranial aneurysm

Interventions

case series:N/A

Eligibility

Sex/Gender

All

Age

18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 75 years; 2. Cerebral aneurysm confirmed by DSA, CTA and MRA; 3. Patients without subarachnoid hemorrhage within 6 months; 4. Patients can take care of themselves with a KPS scale (mRS) > 60 ; 5. Patients' families will sign informed consent and cooperate with clinical treatment and follow-up; 6. Patients do not participate in other similar studies.

Exclusion criteria

Exclusion criteria: 1. Patients with other systemic refractory disease, such as acute heart infarction, renal dysfunction and malignant tumor, etc.; 2. Pregnant or lactating women, or a positive pregnancy test on admission; 3. Patients with other systemic diseases, such autoimmune disease or blood disorder; 4. Patients selected for interventional embolization.

Design outcomes

Primary

Measure	Time frame
Aneurysm enlargement;aneurysm rupture;subarachnoid hemorrhage;VW-MRI enhancement signal;Macrophage level;	—

Countries

China

Contacts

Public ContactWei Zhu

Department of Neurosurgery, Huashan Hospital, Fudan University

drzhuwei@fudan.edu.cn+86 18621120936

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026