Knee joint disease
Conditions
Interventions
Adductor block group A2:Adductor block, ropivacaine and dexmedetomidine analgesia
Femoral nerve block group F1:Femoral nerve block and postoperative analgesia with ropivacaine
Femoral nerve block group F2:Femoral nerve block, ropivacaine and dexmedetomidine analgesia
Adductor block group A1:Adductor block, ropivacaine analgesia
Sponsors
Peking University Shougang Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 79 Years
Inclusion criteria
Inclusion criteria: The patients had informed consent and obtained the approval of the hospital ethics committee; they underwent selective total knee arthroplasty; the age was 18-79 years old; ASA grade I-III; BMI 18-35kg / ?.
Exclusion criteria
Exclusion criteria: Patients who has a history of knee joint trauma, surgery, malignant tumor, primary diseases of lower limb nerve or muscle; serious basic diseases, such as heart, liver, lung, kidney, brain and other organ dysfunction and coagulation function abnormality; history of mental disease; cognitive impairment, unable to complete pain numerical classification (VAS) analgesia score; contraindications of intraspinal anesthesia. Allergic to any one of the drugs used in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rest state VAS score;VAS score of passive activity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Quadriceps femoris muscle strength;Knee flexion;Fall risk assessment;First walk time;72 hours walking distance after operation;Additional times of analgesia pump;C-reactive protein,CRP;interleukin-6, IL-6;procalcitonin, PCT;Postoperative nausea and vomiting;Exhaust time;Postoperative water intake time;Sedation score;Patient satisfaction score;Complications;age;gender;ASA grading;BMI;Preoperative diagnosis;Preoperative complications;Operative time;Anesthesia time;Use of analgesics after operation; | — |
Countries
China
Contacts
Public ContactZhenggang Guo
Peking University Shougang Hospital
Outcome results
None listed