FindTrial
Sign In

Effects of preoperative continuation or withdrawal of ARBs on postoperative complications in elderly patients undergoing noncardiac surgery 30 days after surgery: a prospective randomized controlled trial

Effects of preoperative continuation or withdrawal of ARBs on postoperative complications in elderly patients undergoing noncardiac surgery 30 days after surgery: a prospective randomized controlled trial

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000031248
Enrollment
Unknown
Registered
2020-03-25
Start date
2020-03-31
Completion date
Unknown
Last updated
2020-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hypertension

Interventions

medicine group:to continued use ARBs
Withdrawal group:Stop taking ARBs

Sponsors

Guangdong Provincial Hospital of Tradition Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Patients with hypertension who are to be operated on under general anesthesia by endotracheal intubation; 2. ASA grade II-III, operation grade 3-4; 3. Patients taking ARBs daily to control blood pressure for more than 7 days; 4. 65-85 years old; 5. Patients who need artery puncture for operation.

Exclusion criteria

Exclusion criteria: 1. Patients taking hormone for a long time; 2. Patients with serious heart and lung diseases; 3. Patients with severe liver and kidney dysfunction; 4. Patients with other serious peripheral vascular diseases, intracranial hypertension or celiac hypertension; 5. Patients with intractable uncontrolled hypertension before operation (SBP 200mmhg or DBP 120mmhg); 6. Patients who were treated with pressor drugs recently.

Design outcomes

Primary

MeasureTime frame
adverse outcomes (30 days after surgery);—

Secondary

MeasureTime frame
Incidence of hypotension;—

Countries

China

Contacts

Public ContactJinhe Deng

Guangdong Provincial Hospital of Tradition Chinese Medicine?

459953070@qq.com+86 13751803925

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026