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Study on the effect and mechanism of Buyang Huanwu decoction combined with probiotics on ischemic stroke based on intestinal flora

Study on the effect and mechanism of Buyang Huanwu decoction combined with probiotics on ischemic stroke based on intestinal flora

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000031238
Enrollment
Unknown
Registered
2020-03-25
Start date
2020-04-01
Completion date
Unknown
Last updated
2020-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischemic stroke

Interventions

Sponsors

The Second Affiliated Hospital of Heilongjiang University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients with cerebral infarction confirmed by CT or MRI; 2. Aged 50-75 years; 3. Patients with a course of 15 days to 3 months; 4. Patients with first onset, stable vital signs, clear consciousness, and ability to cooperate with examination and treatment; 5. Patients with unilateral limb motor dysfunction; 6. Patients who voluntarily participated in the study and signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with serious heart, lung, liver, kidney and other organ diseases and various malignant tumors; 2. Patients with allergy to traditional Chinese medicine; 3. Patients who are taking probiotics or prebiotic preparations and have used any antibiotics within one month; 4. Patients who are unable to complete the test or have poor compliance and cannot cooperate due to other reasons; 5. Patients who are participating in other research trials that affect the results of this study.

Design outcomes

Primary

MeasureTime frame
Fugl- Meyer Motor Function Scale;Modified Barthel Index;Intestinal flora detection;Detection of IL-6 by Serial inflammatory factors in Serum;Detection of TNF-a by Serial inflammatory factors in Serum;Detection of hs-CRP by Serial inflammatory factors in Serum;Detection of MMM-9 by Serial inflammatory factors in Serum;Detection of serum SCFAs level;Detection of serum TMAO level;

Countries

China

Contacts

Public ContactLuwen Zhu

Heilongjiang University of Chinese Medicine

383143533@qq.com+86 18646026439

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026