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Cancelled by the investigator A prospective randomized controlled trial of roxadustat for the first recipient to alleviate delayed graft function and acute rejection after renal transplantation

A prospective randomized controlled trial of roxadustat for the first recipient to alleviate delayed graft function and acute rejection after renal transplantation

Status
Unknown
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000031222
Enrollment
Unknown
Registered
2020-03-24
Start date
2020-04-01
Completion date
Unknown
Last updated
2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Delayed graft function after renal transplantation

Interventions

experimental group:Roxadustat Capsules and routine treatment
control group:routine treatment

Sponsors

The Third Affiliated Hospital of Sun Yat-Sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Donors and recipients aged 18-60 years; 2. Patients with indications for renal transplantation; 3. Patients with first kidney transplantation; 4. Renal transplantation with cadaveric donor; 5. Patients willing to sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Renal transplantation with living donor among relatives; 2. Patients with absolute contraindications to renal transplantation; 3. The patients who use the drugs in combination within the non specified scope, especially the drugs that have a great influence on the test results and affect the validity and safety judgment; 4. Patients participating in other clinical trials; 5. Patients with previous history of other organ transplantation; 6. Other situations that the researchers think are not suitable for inclusion.

Design outcomes

Primary

MeasureTime frame
The incidence of delayed graft function, DGF;CD4/CD8;

Secondary

MeasureTime frame
The incidence of acute rejection, AR;panel reactive antibodies, PRA;hemoglobin;Urine volume;BUN;Color Doppler Ultrasound in Patients with Transplanted Kidney;

Countries

China

Contacts

Public ContactQiquan Sun

The Third Affiliated Hospital of Sun Yat-Sen University

sunqiq@mail.sysu.edu.cn+86 18922103587

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026