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Clinical efficacy of Clostridium butyricum in combination with Bacillus coagulans to cure H. pylori infection

Clinical efficacy of Clostridium butyricum in combination with Bacillus coagulans to cure H. pylori infection

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000031220
Enrollment
Unknown
Registered
2020-03-24
Start date
2020-04-01
Completion date
Unknown
Last updated
2020-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Helicobacter pylori infection

Interventions

experimental group A:Bacillus coagulans tablet
experimental group B:Clostridium butyricum capsules
experimental group C:Bacillus coagulans powder
experimental group D:Clostridium butyricum capsules and Bacillus coagulans tablet
experimental group E:Clostridium butyricum capsules and Bacillus coagulans powder

Sponsors

Nanfang Hospital of Southern Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: The patient must meet the following two requirements: 1. Aged >= 18, <= 70 years, both male and female; 2. Patients with positive C13 urea breath test or rapid urease test.

Exclusion criteria

Exclusion criteria: 1. Patients who have used antibiotics, proton pump inhibitors, bismuth agents, probiotics, hormone drugs or non steroidal anti-inflammatory drugs within one month; 2. Patients with gastroduodenal ulcer, hemorrhage, atrophic gastritis, intestinal metaplasia, early or advanced malignant tumor, etc; 3. Pregnancy or lactation; 4. Patients with serious underlying diseases or other diseases that may lead to ineffective treatment; 5. Patients with history of gastrointestinal surgery or other types of recent surgery; 6. Patients with family genetic history, mental disease history, etc; 7. Patients who are participating in other research projects; 8. The patients who are judged by the researcher to be unsuitable to participate in the trial.

Design outcomes

Primary

MeasureTime frame
Helicobacter pylori eradication rate;

Secondary

MeasureTime frame
adverse events;

Countries

China

Contacts

Public ContactYang Bai

Nanfang Hospital of Southern Medical University

13925001665@163.com+86 13925001665

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026