perioperative neurocognitive dysfunction
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Patients aged 65-90 years; 2) ASA 1-2 level; 3) patients undergoing open spinal surgery; 4) Willing to participate in this trial and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1) patients with preoperative disturbance of consciousness; 2) communication barriers; 3) cannot be fixed in the same position for a long time; 4) a history of acupuncture within 6 months; 5) previous history of schizophrenia, Parkinson's disease or epilepsy; 6) obese, with BMI > 35kg/m2; 7) preoperative use of hormones and non-steroidal anti-inflammatory drugs; 8) preoperative use of anticholinergic drugs; 9) patients with preoperative cognitive impairment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the incidence of POD;the incidence of DNR;the incidence of NCD; | — |
Secondary
| Measure | Time frame |
|---|---|
| postoperative complications;hospital stays;Incidence of secondary hospitalization;All-cause mortality; | — |
Countries
China
Contacts
Dongzhimen Hospital Affiliated to Beijing University of Traditional Chinese Medicine