Application of human umbilical cord mesenchymal stem cells derived exosomes in the treatment of patients with dry eye disease

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000031188

Enrollment

Unknown

Registered

2020-03-23

Start date

2020-07-01

Completion date

Unknown

Last updated

2020-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dry eye disease

Interventions

experimental group:hUC-MSC-Exo eye drops

control group:Sodium Hyaluronate Eye Drops

Eligibility

Sex/Gender

All

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 20-60 years; 2. All the patients meet the diagnostic criteria of dry eye; 3. Patients who can follow up on time; 4. Patients who voluntarily join and sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with a history of laser or corneal surgery; 2. Patients with wearing history of contact lenses; 3. Patients with severe immune system diseases; 4. Patients with ocular drug allergy; 5. Pregnant or lactating women; 6. Patients with serious mental or systemic diseases.

Design outcomes

Primary

Measure	Time frame
ocular surface disease index, OSDI;BUT;fluorescein staining, FL;Schirmer I Test;Conjunctival Impression Cytology, CIC;	—

Countries

China

Contacts

Public ContactBi Yanlong

Tongji Hospital Affiliated to Tongji University

biyanlong@tongji.edu.cn+86 13816261568

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026