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Nutritional interventions to improve chemotherapy tolerance in patients with ovarian cancer: a randomized controlled pilot trial

Nutritional interventions to improve chemotherapy tolerance in patients with ovarian cancer: a randomized controlled pilot trial

Status
Unknown
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000031182
Enrollment
Unknown
Registered
2020-03-23
Start date
2021-01-01
Completion date
Unknown
Last updated
2020-06-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ovarian cancer

Interventions

experimental group:Nutrition risk screening and Nutritional intervention

Sponsors

He'nan Cancer Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients with primary ovarian cancer, salpingocarcinoma and primary peritoneal cancer who plan to receive chemotherapy after tumor cell reduction; 2. Patients with residual focus = 3.0 x 10^9 / L, neutrophil count >= 1.5 x 10^9 / L, platelet count >= 100 x 10^9 / L, hemoglobin >= 80 g / L; 6. Organ function is good, biochemical examination meets the following conditions: AST <= 2.5 x upper limit of normal value (ULN), ALT <= 2.5 x upper limit of normal value (ULN), serum total bilirubin <= 1.5 x upper limit of normal value (ULN), creatinine <= 1.5 x upper limit of normal value (ULN); 7. Function status: 0-1 (ECoG); 8. Patients who voluntarily sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with other malignant tumors within 5 years; 2. Patients with other serious diseases that are difficult to control (including atrial fibrillation, angina pectoris, cardiac insufficiency, ejection fraction less than 50%, uncontrolled hypertension, renal insufficiency, uncontrollable infection, etc.); 3. Patients who are being treated with anticancer drugs in other clinical trials; 4. Any unstable condition or situation that may endanger the safety and compliance of patients.

Design outcomes

Primary

MeasureTime frame
whole body fat-free mass index without bone;

Secondary

MeasureTime frame
chemotherapy adverse reaction;Quality of life;Progression-free survival;

Countries

China

Contacts

Public ContactDingxi Li

He'nan Cancer Hospital

lidingxi1@aliyun.com+86 13683831956

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026