acute upper respiratory infection
Conditions
Interventions
seawater group:both basis treatment and nasal irrigation with seawater
control group:basis treatment only
Sponsors
Jiangxi Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. volunteers aged 18 to 65 years, with a duration of symptoms no longer than 72 hours; 2. The acute URI was defined by the presence of at least two of the following 10 symptoms: sneezing, running nose, nasal congestion, headache, myalgia, throat discomfort, sore throat, dysphonia, cough and fever. Symptoms of nasal congestion and running nose should be showed; 3. Patients agreed to participate in the test and sign the informed consent; 4. Well compliance and willing to cooperate to complete the whole clinical trials.
Exclusion criteria
Exclusion criteria: Volunteers were excluded from the study if they met any of the following criteria: 1. pregnancy or breastfeeding; known hypersensitivity to seawater; 2. use of alcohol or illicit drugs; 3. with other?respiratory diseases combined (such as herpangina,suppurative tonsillitis, bronchitis, chronic rhinitis, etc); 4. any current acute disease or uncontrolled exacerbation of chronic disease; 5. serious systemic diseases;need for antiviral therapy to treat influenza A or B infection; 6. need for antibacterial therapy to treat acute respiratory infection; 7. use of medication to treat conditions acquired before inclusion; 8. and participation in another clinical trial less than 3 month before;and patients likely to have poor compliance or that were unlikely to complete the trial, as determined by the investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| effective rate of nasal congestion;effective rate of running nose; | — |
Secondary
| Measure | Time frame |
|---|---|
| symptom score of nasal congestion;symptom score of running nose;symptom score of sleep quality;symptom score of appetite;symptom score of cough;symptom score of fatigue; | — |
Countries
China
Contacts
Public ContactJiang Min
Jiangxi Provincial People's Hospital
Outcome results
None listed