Tooth exogenous pigment
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Good general health, no systemic diseases, can attend the examination at any time during the study; 2. Aged 18-60 years old; 3. There are 12 natural anterior teeth in the mouth, and there is no large backfill or crown prosthesis; 4. Teeth have exogenous pigments, and Lobene spot index >=2; 5. The female shall not be in pregnancy or lactation period; 6. No other whitening toothpaste or measures are used; 7. Did not participate in other similar studies at the same time; 8. Sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. The client has a history of severe oral diseases, chronic diseases or allergies to the research products; 2. Periodontal disease progression or periodontal treatment (including periodontal surgery) in the past year; 3. Tooth trauma, dental fluorosis, tetracycline teeth and other endogenous coloring teeth; 4. The tooth has a large backfill or crown, and is suspected to have pulpitis, caries, enamel cryptic cracks, and the abutment of removable partial denture; 5. Allergic history or special reaction to oral health products or their components; 6. Allergic to toothpaste and its ingredients; 7. Subjects who routinely use an electric toothbrush or adjacent tooth cleaning measures are excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lobene spot index; | — |
Countries
China
Contacts
Peking University Stomatological Hospital Preventive Medicine