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A study for the clinical effect of a whitening toothpaste

A study for the clinical effect of a whitening toothpaste

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000031152
Enrollment
Unknown
Registered
2020-03-23
Start date
2020-05-01
Completion date
Unknown
Last updated
2020-03-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tooth exogenous pigment

Interventions

Intervention group:Brush your teeth twice a day morning and evening using the experimental toothpaste
Control group:Use control toothpaste to brush your teeth twice a day morning and evening

Sponsors

Department of preventive medicine, hospital of stomatology, Peking University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Good general health, no systemic diseases, can attend the examination at any time during the study; 2. Aged 18-60 years old; 3. There are 12 natural anterior teeth in the mouth, and there is no large backfill or crown prosthesis; 4. Teeth have exogenous pigments, and Lobene spot index >=2; 5. The female shall not be in pregnancy or lactation period; 6. No other whitening toothpaste or measures are used; 7. Did not participate in other similar studies at the same time; 8. Sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. The client has a history of severe oral diseases, chronic diseases or allergies to the research products; 2. Periodontal disease progression or periodontal treatment (including periodontal surgery) in the past year; 3. Tooth trauma, dental fluorosis, tetracycline teeth and other endogenous coloring teeth; 4. The tooth has a large backfill or crown, and is suspected to have pulpitis, caries, enamel cryptic cracks, and the abutment of removable partial denture; 5. Allergic history or special reaction to oral health products or their components; 6. Allergic to toothpaste and its ingredients; 7. Subjects who routinely use an electric toothbrush or adjacent tooth cleaning measures are excluded.

Design outcomes

Primary

MeasureTime frame
Lobene spot index;

Countries

China

Contacts

Public ContactWensheng Rong

Peking University Stomatological Hospital Preventive Medicine

rongwensheng@vip.sina.com+86 13681354214

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026