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A Crossover, Single-Blind, Sham-Controlled Study of the Effects of Transcranial Direct Current Stimulation on the Function of Upper Limbs in Preschool Children with Hemiplegic Cerebral Palsy

A Crossover, Single-Blind, Sham-Controlled Study of the Effects of Transcranial Direct Current Stimulation on the Function of Upper Limbs in Preschool Children with Hemiplegic Cerebral Palsy

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000031141
Enrollment
Unknown
Registered
2020-03-23
Start date
2020-04-01
Completion date
Unknown
Last updated
2020-03-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemiplegic cerebral palsy

Interventions

Group 1:active stimulus and then sham stimulus
Group 2:sham stimulus and then active stimulus

Sponsors

Guangzhou Women and Children Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 6 Years

Inclusion criteria

Inclusion criteria: (1) Comply with the diagnostic and classification standards for hemiplegic cerebral palsy in the International Criteria for Diagnosis and Classification of Cerebral Palsy; (2) The age is 3-6 years old, and the child must be able to understand and cooperate with the treatment; (3) Manual Ability Classification System (MACS) rated as I-II; (4) The patient's family or guardian can sign the research informed consent form and cooperate with the treatment to complete the entire research process.

Exclusion criteria

Exclusion criteria: (1) Suffering from other serious diseases not related to cerebral palsy (such as congenital heart disease, leukemia, etc.); (2) Fixed contracture or deformity that affects hand function; (3) uncontrolled epilepsy; (4) Have severe sensory disturbances or vision problems; (5) Contraindications for children with transcranial direct current stimulation (for patients with metal implants in the body, for children with local skin injury or inflammation, for patients with significantly increased intracranial pressure, and for children with hyperalgesia in the stimulation area); (6) have taken muscle relaxants (such as succinylcholine) in the last 3 months, or received a botulinum toxin injection in the last 6 months, or are prepared to receive a botulinum toxin injection during the study period; (7) The affected upper limb has undergone orthopedic surgery.

Design outcomes

Primary

MeasureTime frame
Box and Blocks test;Melbourne assessment 2;Selective Control of the Upper Extremity Scale;modified Ashworth scale;

Countries

China

Contacts

Public ContactXu Kaishou

Guangzhou Women and Children Medical Center

xksyi@126.com+86 18902268610

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 11, 2026