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The application of ultrasonic-guided plane block combined with adjuvant dexmedetomidine in the operation of breast cancer

The application of ultrasonic-guided plane block combined with adjuvant dexmedetomidine in the operation of breast cancer

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000031134
Enrollment
Unknown
Registered
2020-03-22
Start date
2020-03-23
Completion date
Unknown
Last updated
2020-07-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast cancer and postoperative pain

Interventions

Group 2:General anesthesia and plane block of erector ridge muscle (ropivacaine only)
Group 3:General anesthesia and vertical spine muscle plane block (ropivacaine and dexmedetomidine)

Sponsors

The First Affiliated Hospital of Anhui Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Select elective line 90 cases of patients with unilateral breast cancer surgery, aged 18 to 80 years of age, any gender; 2. The American Society of Anesthesiologists classification (American Society of Anesthesiologists, ASA) I and II level; 3. BMI (body mass index, BMI) of 18 to 24 kg/m2.

Exclusion criteria

Exclusion criteria: 1. Severe respiratory and circulatory diseases, such as severe coronary heart disease, copd, etc. 2. Endocrine diseases: pituitary tumor, severe diabetes, increased cortisol, pheochromocytoma, etc. 3. Sinus bradycardia or atrioventricular block; 4. History of allergy to anesthetics. 5. Infection of puncture site; 6. Psychosocial disorders: such as schizophrenia, depression, history of chronic pain medications, history of alcoholism, opioid dependence or inability to understand the visual analogue scale (VAS); 7. History of bleeding disease or abnormal coagulation function; 8. Anxiety or depression; 9. Pregnant or parturient; 10. Other researchers considered the situation unsuitable for this study.

Design outcomes

Primary

MeasureTime frame
Visual Analogue Scale;untoward effect;

Secondary

MeasureTime frame
Ramsay sedation score;Burggrmann comfort scale;Sufentanil dosage;

Countries

China

Contacts

Public ContactLu Yao

The First Affiliated Hospital of Anhui Medical University

luyao-mz@163.com+86 18956564060

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 16, 2026