A Medical records based study for the Association of the Microbiome Metabolite Trimethylamine-N-Oxide with Coronary Atherosclerotic Burden in Patients with Type 2 Diabetes in the Chinese Han Population

The Association of the Microbiome Metabolite Trimethylamine-N-Oxide with Coronary Atherosclerotic Burden in Patients with Type 2 Diabetes in the Chinese Han population

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2000031108

Enrollment

Unknown

Registered

2020-03-22

Start date

2020-03-10

Completion date

Unknown

Last updated

2020-03-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 Diabetes

Interventions

Case series:no

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The patients with T2D who underwent coronary artery angiography (CAG) at the Peking University First Hospital in the years of 2017 and 2018; All the patients were definitively diagnosed as T2D according to Guidelines for the prevention and control of type 2 diabetes in China.

Exclusion criteria

Exclusion criteria: Individuals woth supplement of Vitmain B12/B6 or folic acid; Patient with severe diysfunction of liver or kidney; Patient with prior history of coronary artery bypass grafting (CABG) or percutaneous transluminal coronary intervention (PCI); Patient with history of cardiomyopathy; Patients with malignant tumor of autoimmune diseases; Pregnant or lactating women.

Design outcomes

Primary

Measure	Time frame
Trimethylamine-N-Oxide;	—

Countries

China

Contacts

Public ContactXiaowei Ma

Department of Endocrinology, Peking University First Hospital

xiaowei.ma@pkufh.com+86 13466355560

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026