Asthenia
Conditions
Interventions
1:Middle and low strength knee extensor resistance training
2:Middle quantity and strength knee extensor resistance training
3:Middle and high strength knee extensor resistance training
4:Large and low strength knee extensor resistance training
5:Large and middle strength knee extensor resistance training
Sponsors
Beijing Union Hospital, Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1. Patients who voluntarily participated in the study and signed a written informed consent; 2. Aged >=60 years; 3. Patients who meet the criteria of Fried's asthenia diagnosis.
Exclusion criteria
Exclusion criteria: 1. Patients with MMSE score < 27 and cognitive impairment; 2. Patients with hypertension, diabetes, unstable cardiovascular disease, neuromuscular disease, skeletal muscle malformation, symptomatic rheumatoid arthritis, deep vein thrombosis; 3. Patients with regular physical activity (no more than 3 times a week, 30 minutes each time as the standard); 4. Patients with recent surgery (within 1 month); 5. Patients with a sudden decrease in nutritional intake and a daily intake of < 1600 kcal.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Muscle strength;Muscle Endurance; | — |
Secondary
| Measure | Time frame |
|---|---|
| Physical fitness;Activity ability; | — |
Countries
China
Contacts
Public ContactLai XiaoXing
Beijing Union Hospital, Chinese Academy of Medical Sciences
Outcome results
None listed