FindTrial
Sign In

multimodal neural regulation in the rehabilitation of spinal cord injury: a randomized clinical trial

multimodal neural regulation in the rehabilitation of spinal cord injury: a randomized clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000031095
Enrollment
Unknown
Registered
2020-03-22
Start date
2020-04-01
Completion date
Unknown
Last updated
2020-03-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

spinal cord injury

Interventions

Single target magnetic stimulation group:80%rMTiTBS magnetic stimulation in cortical M1 area corresponding to spinal cord injury combined with routine rehabilitation.
Loop magnetic stimulation group:80%rMTiTBS magnetic stimulation of cortical M1 area corresponding to spinal cord injury combined with 15HzrTMS magnetic stimulation of lower nerve roots of spinal cord
Sham stimulation control group:sham magnetic stimulation combined with routine rehabilitation

Sponsors

Shanghai Tongji Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 65 years old; 2. Grade C/D (ASIA) of spinal cord injury 3. No cognitive impairment or communication disorder, simple mental state examination (MMSE) score above 27; ability of informed consent and understanding; 4. The time of spinal cord injury is more than 6 months.

Exclusion criteria

Exclusion criteria: 1. Patients with severe systemic diseases such as cardiopulmonary diseases who cannot tolerate rehabilitation treatment; 2. Diagnosed with mental illness, major depression (suicidal tendency) or epilepsy, family history of mental illness or epilepsy; 3. Influencing factors of serious systemic diseases such as diabetes and uremia; 4. Severe joint contracture; 5. Suffer from any cause of disturbance of consciousness; 6. According to the safety guidelines, there are contraindications for transcranial magnetic stimulation (TMS) and functional magnetic resonance (fMRI), such as metal foreign bodies or other electronic devices implanted in the body; 7. Application of drugs that change the excitability of the cerebral cortex (antiepileptic drugs, sedative hypnotic drugs, etc.); 8. Unable to receive treatment and regular follow-up in designated hospitals for a long time.

Design outcomes

Primary

MeasureTime frame
LEMS and UEMS;—

Secondary

MeasureTime frame
WISC;MAS;Short-form McGill Pain Questionnaire;Berg Balance Scale;(SCIM-III);Autonomic nerve standard collection table;Neuroelectrophysiological feedback and detection;fMRI brain function;—

Countries

China

Contacts

Public ContactDongsheng Xu

Shanghai Tongji Hospital

dxu0927@163.com+86 13017103619

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026