Obstructive sleep apnea
Conditions
Sponsors
Xiang'an Hospital of Xiamen University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. ASA physical status I~III; 2. Adult patients (Age>18 y); 3. Patents known for non-treated OSA or suspected of having a high risk of OSA indicated by STOP-BANG score*>3; 4. Patients scheduled to undergo open or laparoscopic urologic and digestive surgery; 5. Anticipated operation time>2 h.
Exclusion criteria
Exclusion criteria: 1. History of difficult airway or Mallampati airway grades>3 that would preclude standard induction of anesthesia; 2. Patients known for treated OSA; 3. Any contraindication to epidural analgesia; 4. Laparoscopic surgery; 5. Emergency surgery; 6. Severe respiratory disease (i.e., chronic obstructive pulmonary disease, asthma, pulmonary fibrosis); 7. Severe cardiovascular disease; 8. Severe psychiatric or neurologic disease; 9. Severe hepatic or renal disease (baseline ALT, AST, BUN and/or creatinine>1.5); 10. History of allergy or contraindication to anesthetic agents; 11. History of delirium; 12. History of hallucinations; 13. Potential risk for malignant hyperthermia (family history); 14. History of chronic opiates or benzodiazepine abuse in last 90 d; 15. History of chronic alcohol abuse in last 90 d; 16. Pregnancy and breast-feeding women; 17. Inability to consent; 18. Refusal.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of post-anesthesia respiratory depression in PACU; | — |
Secondary
| Measure | Time frame |
|---|---|
| Recovery times;Incidence of emergence delirium in the PACU;Incidence and degree of PONV as assessed by a VAS in the PACU and 12 to 24 h postoperatively;Rescue analgesia in PACU;The duration of PACU and hospital stay;Incidence of respiratory complications 24 h postoperatively; | — |
Countries
China
Contacts
Public ContactHou Lichao
Xiang'an Hospital of Xiamen University
Outcome results
None listed