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Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients requiring primary total hip arthroplasty due to severe hip osteoarthritis, femoral head necrosis, and secondary osteoarthritis due to developmental hip dysplasia; 2. Aged between 18 and 80 years; 3. Patients with preoperative American Society of anesthesiologists (ASA) grading (anesthesia risk assessment) of I ~ III; 4. Patients with body mass index less than 30 kg / m2.
Exclusion criteria
Exclusion criteria: 1. Patients who are allergic to the drugs used in the experiment; 2. Patients with language disorders and inability to complete various questionnaire scores; 3. Patients with limb neuropathy on the operative side; 4. With mentally ill; 5. One-stage bilateral total hip arthroplasty; 6. With severe osteoporosis; 7. With a history of hip surgery prior to the initial replacement; 8. Patients with secondary osteoarthritis after treatment of hip infection; 9. Patients with iliac wing width or acetabulum posterior wall bone defect; 10. Alcoholic or long-term opioid users; 11. Patients with previous gastrointestinal ulcer.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative dosage of remedial morphine hydrochloride;Time of first postoperative analgesia;VAS pain score;QoR -15 scale;Quadriceps strength;Daily walking distance;Time to first straight leg raise;The duration of hospital stay;Incidence of postoperative complications;Oxford hip score;UCLA Activity-Level Rating; | — |
Countries
China
Contacts
West China Hospital of Sichuan University