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Perioperative immune prediction and intervention of tumor patients undergoing surgery during the novel coronavirus pneumonia (COVID-19) outbreak period

Perioperative immune prediction and intervention of tumor patients undergoing surgery during the novel coronavirus pneumonia (COVID-19) outbreak period

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000031023
Enrollment
Unknown
Registered
2020-03-21
Start date
2020-03-16
Completion date
Unknown
Last updated
2020-03-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cancer

Interventions

Sponsors

Hu'nan Cancer Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) aged 18-60 years; (2) BMI in the normal range (1+/-20%); (3) diagnosis of lung cancer, breast cancer, cervical cancer, colorectal cancer, with surgical indications, no distant metastasis; (4) ASA grade I-II; (5) no thymosin A1, Chinese Medicine (Bazhen Tang) use contraindications; (6) before the test, the patients or their legal representatives understand and voluntarily sign the ethics Informed consent approved by the Committee.

Exclusion criteria

Exclusion criteria: (1) had participated in other clinical trials within 4 weeks before the start of this study; (2) used albumin and immunoenhancer drugs within 15 days before operation; (3) had a history of coronavirus infection, direct or indirect exposure, had fever, cough; (4) had previous immune deficiency; (5) had congenital metabolic abnormalities and other diseases; (6) Patients with autoimmune diseases and infections; (7) pregnant and lactating women; (8) who were not willing to participate in the study for any reason.

Design outcomes

Primary

MeasureTime frame
postoperative complication;occupancy rate of intensive care unit;2-year tumor-free survival and overall survival;

Secondary

MeasureTime frame
prognostic nutritional index;immune-inflammationindex;CD4+T cell;CD8+T cell;the ratio of CD4/CD8;Treg cell;CD44+T cell;TNF-alpha;IL-17;

Countries

China

Contacts

Public ContactYang Jinfeng

Hu'nan Cancer Hospital

315977705@qq.com+86 13875985950

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026