Effects of different doses of dexmedetomidine on intraoperative neurophysiological monitoring in patients undergoing neurosurgical spinal surgery
Conditions
Interventions
experimental group:Dexmedetomidine
control group:Normal saline
Sponsors
Beijing Friendship Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-65 years; 2. ASA I-II; 3. Patients who need electrophysiological monitoring for elective spinal surgery.
Exclusion criteria
Exclusion criteria: 1. Those with congenital neurological dysfunction; 2. Preoperative oral antidepressants, sedatives, analgesics or alcoholics; 3. The kidney, heart, liver and other functional organs are seriously disabled; 4. Family members or patients refused to participate in the study; 5. The patients were not monitored during the operation due to various reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Somatosensory evoked potential amplitude;Somatosensory evoked potential latency;motor evoked potential amplitude;Motor evoked potential latency; | — |
Secondary
| Measure | Time frame |
|---|---|
| Dosage of general anesthetic drugs;Postoperative complications; | — |
Countries
China
Contacts
Public ContactLixin An
Beijing Friendship Hospital, Capital Medical University
Outcome results
None listed