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Comparison of the efficacy and safety of sedation protocols with the use of dexmedetomidine-remifentanil and propofol-remifentanil during percutaneous closure of atrial septal defects

Comparison of the efficacy and safety of sedation protocols with the use of dexmedetomidine-remifentanil and propofol-remifentanil during percutaneous closure of atrial septal defects

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000030969
Enrollment
Unknown
Registered
2020-03-20
Start date
2020-03-16
Completion date
Unknown
Last updated
2020-03-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia for percutaneous closure of atrial septal defects

Interventions

D-R group:dexmedetomidine combined with remifentanil
P-R group:propofol combined with remifentanil are

Sponsors

Fujian Medical University Union Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Patients with secundum atrial septal defects (ASD);Left-to-right intracardiac shunt; aged >=18 years old; American society of anesthesiologists(ASA)class <IV.

Exclusion criteria

Exclusion criteria: Coexisting other cardiovascular malformations; Bi-directional or right-to-left intracardiac shunt; STOP-Bang score >=3; Heart rate 100 beats/min; Other known severe arrhythmias; Severe renal, hepatic, or heart failure; Known drug allergies; A history of drug abuse; incapable of communicate

Design outcomes

Primary

MeasureTime frame
The incidence of adverse events;the outcome of arterial blood gas analysis;induction time and recovery time;Pain level;

Secondary

MeasureTime frame
Patients' and physicians' satisfaction of sedation;

Countries

China

Contacts

Public ContactGuican Zhang

Fujian Medical University Union Hospital

zhangguican123@163.com+86 13509393312

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026