Severe Brain Injuiry
Conditions
Interventions
open endotracheal suction group:The open suctioning group will use a single ordinary suction tube (Pacifi, China) for sputum suction after detachment from the ventilator.
closed endotracheal suction group:the closed sputum suction tube was inserted from one end of the Y-connector of tracheal intubation for intratracheal suction.
Sponsors
Children's hospital of nanjing medical university
Eligibility
Sex/Gender
All
Age
1 Years to 18 Years
Inclusion criteria
Inclusion criteria: 1. Children aged 28 days to 18 years; 2. Patients whose diseases meet the relevant diagnostic criteria [1,2] in the 4th edition of American guidelines for the diagnosis and treatment of severe brain injury; 3. Children who will receive mechanical ventilation with ventilator; 4. Children with no other severe organ dysfunction, such as congenital heart disease; 5. The guardian or relatives will be informed and agree to participate in this present study.
Exclusion criteria
Exclusion criteria: 1. Children with pneumothorax, atelectasis, or other serious congenital diseases or respiratory infections; 2. Children or the guardians will not consent to participate in this present study and sign the informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| he ICP (mmHg) level before suctioning, at the end of suctioning, and at 5 and 10 minutes after suctioning;;he pulse oxygen saturation (SpO2,%) and heart rate (times/min) before suctioning, at the end of suctioning, and at 5 and 10 minutes after suctioning; | — |
Secondary
| Measure | Time frame |
|---|---|
| The estimated sputum volume (ml) for each suction;the incidence of ventilator-associated pneumonia(VAP); Duration of mechanical ventilation (days);The length of ICU stay (days).; | — |
Countries
China
Contacts
Public ContactLi Wei
Children's Hospital of Nanjing Medical University
Outcome results
None listed