None
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Healthy subjects: (1) Aged 20-80 years old; (2) life-long non-smokers; (3) No Long-term exposure to harmful gas or particles; (4) No history or symptoms of chronic cardiopulmonary diseases (chronic bronchitis, asthma, lung cancer, pulmonary fibrosis, pulmonary tuberculosis, chronic heart diseases, etc.); (5) No abnormal findings on physical examination; (6) No upper or lower respiratory infections within the last 4 weeks before the visit. 2. Chronic obstructive pulmonary disease patients: (1) Clinically diagnosed as COPD according to GOLD 2019; (2) Aged 40-80 years old; (3) Outpatients; (4) No exacerbation within the last 4 weeks before the visit; (5) With available spirometry reports in the first affiliated hospital of Guangzhou Medical University in 2016 to 2019; 3. Asthma patients: (1) Clinically diagnosed as Asthma according to GINA 2019; (2) Aged 20-80 years old; (3) Outpatients; (4) With available spirometry reports in the first affiliated hospital of Guangzhou Medical University in 2016 to 2019.
Exclusion criteria
Exclusion criteria: 1. Healthy subjects: (1) Abnormal findings on chest radiography; (2) With diseases or histories of surgery potentially affecting lung function; (3) Using ß-blocker treatment; (4) Pregnant or epileptic. 2. Chronic obstructive pulmonary disease and asthma patients: (1) With histories of surgery potentially affecting lung function; (2) Using ß-blocker treatment; (3) Pregnant or epileptic.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Difference between lung age and chronological age (?lung age); | — |
Primary
| Measure | Time frame |
|---|---|
| Forced expiratory volume in 1 second (FEV1);Forced vital capacity (FVC);FEV1/FVC;Age;Height; | — |
Countries
China
Contacts
The First Affiliated Hospital of Guangzhou Medical University/Guangzhou Institute of Respiratory Health