Novel Coronavirus Pneumonia (COVID-19)
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged >=18 years old; 2. The person, who is diagnosed as COVID-19 according to the 'Diagnosis and treatment of novel coronavirus pneumonia (trial edition 5)', is treated with de-isolation and meets hospital discharge criteria: Temperature returned to normal over 3 days, respiratory symptoms improved obviously, two consecutive respiratory tract pathogenic nucleic acid detection negative (sampling time interval at least 1 day), can be removed from isolation and discharged or transferred to the corresponding department to treat other diseases; 3. The gastrointestinal structure and function of the patient are permitted and can be used safely and should be actively supported by enteral nutrition.
Exclusion criteria
Exclusion criteria: 1. Gestational female patients; 2. Patients with allergic constitution, specifically with a history of allergies to these three intervention drugs; 3. Patients with other malignant diseases such as malignant tumours, chronic liver or kidney diseases, and reaching the end stage; 4. Patients with known psychiatric disorders; 5. Patients withdrawing from other clinical trial within 4 weeks.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Albumin;Cellular immune indicators (total lymphocyte count (TLC) and T lymphocyte subsets (CD3, CD4)); | — |
Secondary
| Measure | Time frame |
|---|---|
| Recurrence rate of COVID-19.;Height;Weight;body mass index;upper arm circumference;triceps fold thickness;transferrin concentration;prealbumin concentration;C-reactive protein;humoral immune indicators (serum IgA, IgG, IgM);inflammatory factors (including IL-2, IL-4, IL-6, IL-10, TNF-alpha, TNF-gama, etc.); | — |
Countries
China
Contacts
HwaMei Hospital, University of Chinese Academy of Sciences