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Effect of Jiangtangxiaozhi Capsule on intestinal flora in obese IGT patients

Study on the effect of Jiangtangxiaozhi Capsule on the intestinal flora of obese IGT patients by the determination of LPS and GLP-1

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000030915
Enrollment
Unknown
Registered
2020-03-17
Start date
2020-05-01
Completion date
Unknown
Last updated
2020-03-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Impaired glucose tolerance

Interventions

Sponsors

Xiyuan Hospital,China Academy of Chinese Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-60 years old; 2. IGT and obesity diagnostic criteria were met; 3. No antibiotics, probiotics and any other Chinese and Western medicine for digestive system diseases were used within 1 month before treatment; 4. There was no history of chronic gastrointestinal disease and hepatobiliary infection; 5. Signed informed consent.

Exclusion criteria

Exclusion criteria: 1. ALT and AST were 1.5 times higher than the upper limit of normal value and creatinine was higher than the upper limit of normal value; 2. TG>5.7mmol/l; 3. Patients with severe circulatory system diseases, respiratory system diseases, immune system diseases, malignant tumors and other serious diseases; 4. Those who have obvious diet preference or single diet habit; 5. Those who take metformin, acarbose and other Western medicine and have the effect of reducing blood sugar; 6. Participants in other clinical trials within 3 months; 7. Mental illness patients; 8. Pregnant or lactating women; 9. Those who are intolerant to jiangtangxiaozhi capsule or simulant.

Design outcomes

Primary

MeasureTime frame
Insulin resistance index;lipopolysaccharide;Glucagon like peptide-1;DNA extraction of intestinal flora gene;blood fat;

Countries

China

Contacts

Public ContactZou Benliang

Xiyuan Hospital,China Academy of Chinese Medical Sciences

forestzbl@sina.com+86 13522092745

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026