acute ischemic stroke
Conditions
Interventions
experimental group:aspirin and clopidogrel combined with DL-3 n-butylphthalide
control group:aspirin and clopidogrel
Sponsors
Heze Municipal Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: The following criteria were met: (1) the patient was 40-80 years old; (2) patients with clinically diagnosed acute ischemic stroke began to enter the study within 48 hours prior to the diagnosis; (3) patients scored 5 to 20 on the stroke scale of the national institutes of health (nih); (4) computed tomography (CT) scan is required to exclude the patient's intracranial hemorrhage; (5) no communication or impaired cognitive function (MMSE score >15)
Exclusion criteria
Exclusion criteria: The exclusion criteria were as follows: (1) patients with a transient ischemic attack; (2) patients with a history of depression,psychosis, or severe substance abuse; (3) patients have been taking antidepressants within 2 weeks prior to the stroke; (4) patients with possible concurrent depression; (5) cardiogenic embolism and anticipated revascularisation of cerebral arteries; (6) a stroke history with a score 2 on the modified Rankin score (mRS); (7) severe liver or renal dysfunction; (8) major disorders associated with an increased risk of bleeding; (9) contraindications to antiplatelet treatments; (10) the use of other antiplatelet drugs during the trial period.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hamilton Depression Scale;the Hamilton Anxiety Scale;the Barthel index of activities of daily living;Modified Rankin Scale scores;the National institutes of health stroke scale; | — |
Countries
China
Contacts
Public ContactChen Yankun
Heze Municipal Hospital
Outcome results
None listed