Low back pain
Conditions
Interventions
Sponsors
Shanghai Tongji Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Drug therapy combined with rehabilitation training group: 1. Untreated patients with low back pain; 2. The lumbar function is good and can withstand the actions required by the test. 3. Able to cooperate in completing all research steps; 4. Agree to participate in the test. Simple rehabilitation training group: 1. Untreated patients with low back pain; 2. The lumbar function is good and can withstand the actions required by the test; 3. Able to cooperate in completing all research steps; 4. Agree to participate in the test. Normal group: 1. After CT examination, one imaging expert and one spinal surgery expert confirmed that there was no lumbar spine injury or paraspinal muscle disease; 2. Able to cooperate in completing all research steps; 3. Patients who can't be radiographed.
Exclusion criteria
Exclusion criteria: Drug therapy combined with rehabilitation training group: 1. Has a history of back surgery; 2. With spinal malignant tumor, infection, fracture, cauda equina syndrome or ankylosing spondylitis or other inflammatory diseases; Spinal deformity, such as lumbar spondylolisthesis; 3. With other systemic diseases, such as diabetes and kidney diseases; 4. Patients who have received lumbar muscle training in the past year; 5. Taking NSAIDs within 10 days; 6. Allergy to celecoxib or any other component in the drug; 7. Sulfanilamide allergy; 8. Patients with active peptic ulcer/hemorrhage; 9. With severe osteoporosis, hypertension and heart disease. Simple rehabilitation training group: 1. With history of back surgery; 2. With spinal malignant tumor, infection, fracture, cauda equina syndrome or ankylosing spondylitis or other inflammatory diseases; Spinal deformity, such as lumbar spondylolisthesis; 3. With other systemic diseases, such as diabetes and kidney diseases; 4. Patients who have received lumbar muscle training in the past year; 5. Taking NSAIDs within 10 days; 6. With severe osteoporosis, hypertension and heart disease. Normal group: 1. With other systemic diseases such as diabetes, myasthenia gravis, etc.; 2. Patients with recent fever or intestinal or bladder dysfunction; 3. Women of childbearing ability who has planned or suspected pregnancy due to possible harm to the fetus caused by X-rays; 4. Patients with contraindications of MRI; 5. With lumbar deformity; 6. With history of lumbar spine injury or chronic diseases of paraspinal muscles 7. With chronic lumbar pain.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Global spine parameters; | — |
Countries
China
Contacts
Public ContactCheng Liming
Department of Spine Surgery, Tongji Hospital
Outcome results
None listed