The changes of respiration and circulation and Disease Postoperative Pulmonary Complications
Conditions
Interventions
Group A:VT: 6ml/kg, frequency 12-18/min. Pulmonary retentions for 30 s, only once
Group B:VT: 6ml/kg, frequency 12-18/min. Pulmonary retentions for 10 s, three times
Group C : VT: 6ml/kg, frequency 12-18/min. No pulmonary duplication
Sponsors
The General Hospital of Western Theater Command
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) ASA grade I-III, Patients undergoing holmium laser lithotripsy under elective general anesthesia,the operation time was 1 to 3 hours; (2) Aged 18-65 years, Body mass index, BMI 18-30 kg/m2; (3) Preoperative lung function was normal; (4) Pregnancy test negative for women of childbearing age; (5) Voluntarily accepted general anesthesia and participated in the study.
Exclusion criteria
Exclusion criteria: (1) History of previous serious neuromuscular diseases, cardiovascular diseasesliver and kidney dysfunction (2) Patients with severe chest diseases and history of chronic respiratory diseases ; (3) Alcoholics, long-term sedatives, opioid addicts; (4) Those who have participated in other drugs clinical researches in recent three months; (5) With mental system disease, Normal ability of communication; (6) With previous history of severe allergy; (7) Researchers evaluate who is not suitable to participate in this clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative pulmonary complications, include respiratory failure, pulmonary infection, pleural effusion, atelectasis, pneumothorax, bronchospasm, aspiration pneumonia, and pulmonary embolism Intraoperative circulatory indicators include: HR, SBP, DPB, MBP;arterial blood gas analysis;Heart rate (HR), Mean arterial pressure (Mbp); | — |
Secondary
| Measure | Time frame |
|---|---|
| Tidal volume (TV);Airway peak;Airway mean pressure (Pmean);Respiratory rate (RR);Breathe out at the end of the carbon dioxide (PetCO2); | — |
Countries
China
Contacts
Public ContactWu Wei
The General Hospital of Western Theater Command
Outcome results
None listed