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Simulation and optimization of electrical stimulation strategy for peripheral nerve injury based on finite element method

Simulation and optimization of electrical stimulation strategy for peripheral nerve injury based on finite element method

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000030790
Enrollment
Unknown
Registered
2020-03-14
Start date
2020-03-04
Completion date
Unknown
Last updated
2021-06-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Peripheral nerve injury

Interventions

Group 1:Finite element optimization of electrical stimulus scheme
Group 2:non-optimal electrical stimulation
Group 3:nromal rehabilitation

Sponsors

Tianjin Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
5 Years to 80 Years

Inclusion criteria

Inclusion criteria: In this study, nerve injury was used as a clue, and a computer finite element model was used as a guide to optimize the treatment parameters of local electrical stimulation. 1. Patients with upper extremity trauma for 2-3 months; 2. Patients with nerve injury identified by electromyography; 3. With no definite nerve fracture was found in surgical exploration or ultrasonic examination; 4. Ultrasonic examination showed no obvious nerve compression.

Exclusion criteria

Exclusion criteria: 1. With heart, lung, brain, liver, kidney and other major organ diseases (such as: heart failure and acute stage of heart disease, acute and chronic hepatitis, acute and chronic nephritis, acute stage of stroke, tuberculosis, asthma, chronic bronchitis, severe anemia, etc.); 2. With recent (within 1 year) metabolic diseases (such as hyperthyroidism, hypothyroidism and edema); 3. Persons with physical disability or limb deformity; 4. Patients with acute diseases who have suffered from high fever, diarrhea and other acute diseases in the near future (within 1 month) and have not recovered their physical strength at present; 5. With fractures or dislocations of limbs or joints within the last six months; 6. The patient has previous electrical stimulation or received professional sports training; 7. With history of allergic reaction to electric stimulation; 8. With pacemaker in body.

Design outcomes

Primary

MeasureTime frame
electromyography;ultrasound;standards of Chinese Medical Society of Hand Surgery of upper limb assessment protocol;

Secondary

MeasureTime frame
grip strength;pinch strength;two-point discrimintion;deep sensation;

Countries

China

Contacts

Public ContactQi Li

Tianjin Hospital

liqi_82@126.com+86 15022095665

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026