Novel Coronavirus Pneumonia (COVID-19)
Conditions
Interventions
transnasal high-flow oxygen therapy:prone position ventilation
noninvasive mechanical ventilation:prone position ventilation
invasive mechanical ventilation:prone position ventilation
Sponsors
Shandong Provincial Chest hospital
Eligibility
Sex/Gender
All
Age
14 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Patients who were diagnosed as COVID-19 by nucleic acid test; 2. aged 14 years or more; 3. diagnosis of ARDS according to Berlin definition.
Exclusion criteria
Exclusion criteria: 1. Hemodynamic instability: Cardiac pacemaker inserted in the last 2 days or life-threatening arrhythmias or circulatory disorders (use of large doses of vasoactive drugs); 2. Intracranial pressure >30 mm Hg or cerebral perfusion pressure <60 mmHg; 3. Massive hemoptysis requiring an immediate surgical or interventional radiology procedure; 4. Tracheal surgery or sternotomy during the previous 15 days; 5. Serious facial trauma or facial surgery; 6. Deep venous thrombosis treated for less than 2 days; 7. Anterior chest wall placed closed thoracic drainage device; 8. Open wound of abdominal cavity; 9. Unstable spine; 10. femur or pelvic fractures; 11. Pregnant women; 12. Use of extracorporeal membrane oxygenation (ECMO) before inclusion; 13. Chronic respiratory failure requiring oxygen therapy or non-invasive ventilation(NIV); 14. Previous inclusion in the present study; 15. Opposition from next of kin.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PaO2;PaCO2; | — |
Countries
China
Contacts
Public ContactFenglin Liu
Shandong Provincial Chest Hospital
Outcome results
None listed