Breast Cancer
Conditions
Interventions
Sponsors
Southwest Hospital, Army Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1) Age: 18-70 years old; 2) Histologically and/or cytologically confirmed breast cancer; 3) Initial treatment;no breast or axillary surgery before treatment; 4) Preoperative physical and auxiliary examinations showed that the axillary fossa had no obvious structural abnormal swelling of the lymph nodes and no distant metastasis; 5) Patients who voluntarily receive three tracers of SLN; 6) Patients must have the ability to understand and voluntarily sign the informed consent; 7) ECOG physical status score is 0 to 2; 8) Subjects have no major organ dysfunction, laboratory test indicators must meet the following requirements: Hematology: WBC >= 3.5 x 10^9/L, neutrophils >= 2.0 x 10^9/L, platelet count >= 100 x 10^9/L, hemoglobin >= 95g/L. Liver function: serum bilirubin was 1.5 times lower than the maximum normal value; ALT and AST are 1.5 times lower than maximum normal. Renal function: creatinine clearance rate >= 45mL/min; Heart function: basically normal.
Exclusion criteria
Exclusion criteria: 1) Patient had undergone surgery in the axillary region to destroy lymphatic drainage in this area; 2) Multi- or multi-focal breast cancer; 3) Axillary lymph node metastasis has been found clinically; 4) Breast cancer patients during pregnancy; 5) Lactating breast cancer patients; 6) Patients with other system diseases or malignant tumors that cannot be operated; 7) Researchers believe that other reasons are not suitable for clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sentinel lymph node detection rate;Local and systemic side effects;Sensitivity;Distant metastasis;Survival situation; | — |
Countries
China
Contacts
Public ContactXiaowei Qi
Southwest Hospital, Army Medical University
Outcome results
None listed