Canceled by the investigator. Low-dose esketamine for cesarean section effects on postpartum depression

Low-dose esketamine for cesarean section effects on postpartum depression

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000030698

Enrollment

Unknown

Registered

2020-03-10

Start date

2020-04-01

Completion date

Unknown

Last updated

2023-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postpartum depression

Interventions

control group:5ml of 0.9% physiological saline solution

ketamine group:Intravenous injection of esketamine 0.25mg / kg, dissolved in 5ml colorless transparent solution with 0.9% physiological saline.

Butorphanol Tartrate group:Conventional injection of Noyang 0.5mg, dissolved in 0.9% saline 5ml.

Eligibility

Sex/Gender

Female

Age

20 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Women who gave birth by cesarean section at Shengjing Hospital; 2. Maternal aged 20-40 years; 3. Gestational aged 28-42 weeks; 4.Edinburgh postoperative depression scale score >=10; 5.Pregnancy without assisted reproductive means; 6.Firstborn.

Exclusion criteria

Exclusion criteria: 1. The mother has a history of depression; 2.The mother has experienced domestic violence; 3. The mother has severe obstetric complications or serious underlying diseases; 4. The newborn has a severe genetic or congenital disease; 5. Multiple pregnancy; 6. Weight 100 kg, height 180cm.

Design outcomes

Primary

Measure	Time frame
Depression related indicator;	—

Secondary

Measure	Time frame
basic information;intraoperative;postoperative;	—

Countries

China

Contacts

Public ContactPing Zhao

Department of Anesthesiology, Shengjing Hospital, China Medical University

zhaop@sj-hospital.org+86 18940258971

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026