Skip to content

The function of theTim-3-Gal-9 pathway in the immune microenvironment of the maternal-fetal interface in spontaneous preterm birth

The function of theTim-3-Gal-9 pathway in the immune microenvironment of the maternal-fetal interface in spontaneous preterm birth

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000030695
Enrollment
Unknown
Registered
2020-03-10
Start date
2017-01-01
Completion date
Unknown
Last updated
2020-03-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

spontaneous preterm birth

Interventions

spontaneous preterm birth (SPB) versus normal healthy pregnancies:Nil

Sponsors

Subei People's hospital ,Jiangsu,China
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. a single pregnancy child; 2. Voluntary informed consent.

Exclusion criteria

Exclusion criteria: 1. Twin or multiple pregnancy; 2. A history of repeated miscarriage or premature delivery; 3. A history of acute and chronic diseases (such as hypertension, diabetes, heart disease, endocrine and metabolic diseases, liver and kidney diseases, rheumatism, rheumatoid, lupus and other autoimmune diseases); 4. Infection and inflammation; 5. Other complications of pregnancy (such as fetal growth restriction, placenta previa, placental abruption, intrahepatic cholestasis during pregnancy, gestational diabetes mellitus, preeclampsia and eclampsia); 6. A history of infection (e.g. hepatitis, syphilis, etc.); 7. Bad habits such as tobacco and alcohol; 8. Patients participating in other clinical trials; 9. The researchers considered it inappropriate for clinical subjects for other reasons.

Design outcomes

Primary

MeasureTime frame
Tim-3 and Gal-9 protein levels of decidual and embryolemma tissues;IFN-gama, IL-17 and IL-10 level;

Countries

China

Contacts

Public ContactMin Jiang

Subei People's Hospital

jiangmin871101@163.com+86 18051061877

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026