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A prospective randomized controlled clinical study of Montelukast in the treatment of postoperative lymphedema of breast cancer

A prospective randomized controlled clinical study of Montelukast in the treatment of postoperative lymphedema of breast cancer

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000030676
Enrollment
Unknown
Registered
2020-03-09
Start date
2020-03-31
Completion date
Unknown
Last updated
2020-04-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lymphedema

Interventions

experimental group:complete decongestive therapy combined with Montelukast

Sponsors

The Fifth Affiliated Hospital of Sun Yat-Sen University
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. The pathological diagnosis was confirmed as breast cancer, which was treated with radical mastectomy and radiotherapy and chemotherapy; 2. The patients who met the criteria of lymphedema of upper extremity after mastectomy in breast oncology. The patients who had postoperative lymphedema and the difference between arm circumference and healthy side was more than 2cm. And according to the criteria of lymphedema of stage I-III formulated by the international lymphatics Association; 3. The patients who were over 18 years old; 4. Have certain reading and writing ability; 5. Sign the informed consent voluntarily.

Exclusion criteria

Exclusion criteria: 1. Patients with distant metastasis of tumor; 2. Patients with serious complications such as systemic infection and severe anemia; 3. Patients with local rupture and bleeding tendency; 4. Patients with edema caused by thrombus and other factors; 5. Pregnant or lactating women; 6. Patients with related drug allergy; 7. Patients with previous history of mental illness or dementia or poor compliance.

Design outcomes

Primary

MeasureTime frame
Upper limb circumference;CD4+T cell;CD8+T cell;Th cell subsets;

Countries

China

Contacts

Public ContactLin Ziling

The Fifth Affiliated Hospital of Sun Yat-Sen University

13928021860@139.com+86 13928021860

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026