Study for the efficacy and safety of dizosin in postoperative analgesia in children

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000030666

Enrollment

Unknown

Registered

2020-03-09

Start date

2020-04-01

Completion date

Unknown

Last updated

2020-03-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pain

Interventions

D1:Dezocine8ug/kg/h+Midazolam/2ug/kg/min

D2:Dezocine12ug/kg/h+Midazolam/2ug/kg/min

D3:Dezocine16ug/kg/h+Midazolam/2ug/kg/min

D4:Dezocine20ug/kg/h+Midazolam/2ug/kg/min

F:Fentanyl2ug/kg/h+Midazolam/2ug/kg/min

M:Morphine20ug/kg/h+Midazolam/2ug/kg/min

Eligibility

Sex/Gender

All

Age

No minimum to 7 Years

Inclusion criteria

Inclusion criteria: 1. Aged 0 to 7 years; 2. Children admitted to PICU are postoperative patients of ASA grade I-II, including patients after cardiothoracic surgery, patients after brain surgery, patients after orthopedics, And patients after general surgery.

Exclusion criteria

Exclusion criteria: 1. Children with pacemaker after operation; 2. Children with heart failure and infection after operation; 3. Children with ICU stay <24h; 4. Children with history of opioid taking and allergy; 5. Children with mental and neurological diseases; 6. Children with severe liver and kidney dysfunction; 7. Children who could not cooperate with postoperative scores.

Design outcomes

Primary

Measure	Time frame
breathe;heart rate;SPO2;lactic acid;blood glucose;Serum cortisol;	—

Countries

China

Contacts

Public ContactXu Feng

Children's Hospital Affiliated to Chongqing Medical University

xufeng9899@163.com+86 23-63622664

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026