Retroperitoneal laparoscopic kidney surgery
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) patients undergoing retroperitoneal laparoscopic single kidney surgery under elective general anesthesia, who are expected to receive PCA pump (the drug in the pump is oxycodone) after surgery; (2) for patients undergoing endotracheal intubation under static inhalation combined with general anesthesia, ASA grades from I to II; (3) aged from 18 to 65 years; (4) body mass index (BMI): 18-24 kg/m2; (5) participate in the clinical trial voluntarily and sign the informed consent.
Exclusion criteria
Exclusion criteria: (1) analgesic drugs and alcohol were used 24 h before surgery; (2) refuse to participate in the study and cannot cooperate with the operation; (3) patients with severe hypertension, heart disease, diabetes or severe liver and kidney dysfunction before surgery; (4) local anaesthetic allergy; (5) puncture contraindication, including skin damage, infection or coagulation dysfunction at the puncture site; (6) pregnant or nursing women; (7) participate in other clinical trials within 3 months prior to study inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total dose of oxycodone for 48 hours; | — |
Secondary
| Measure | Time frame |
|---|---|
| Opioid dosage during surgery;At 2 h, 6 h, 12 h, 24 h, 36 h, and 48 h after surgery, NRS score of resting and NRS score of exercise was obtained;Remedial treatment occurred within 48 h after surgery;Safety evaluation (occurrence of hypoemia, hypomyosis, nausea and vomiting, respiratory depression, drowsiness, etc. within 48 hours after operation); | — |
Contacts
Department of Anesthesiology, Chifeng Municipal Hospital