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The intervention of acupuncture and traditional Chinese medicine 'pre cultivate its damage' on IVF / ICSI-ET outcome of elderly dor women with kidney deficiency and the regulation of microbiome and local immune response of cervicovaginal: a prospective cohort study

The intervention of acupuncture and traditional Chinese medicine 'pre cultivate its damage' on IVF / ICSI-ET outcome of elderly dor women with kidney deficiency and the regulation of microbiome and local immune response of cervicovaginal: a prospective cohort study

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000030644
Enrollment
Unknown
Registered
2020-03-08
Start date
2020-07-01
Completion date
Unknown
Last updated
2020-03-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Interventions

Sponsors

Tongji Hospital Affiliated to Tongji University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
35 Years to 42 Years

Inclusion criteria

Inclusion criteria: 1. Aged between 35 and 42 years old; 2. Patients with indications for IVF / ICSI-ET; 3. Patients meeting the diagnostic criteria of Dor; 4. Patients in accordance with the diagnosis of kidney deficiency syndrome in traditional Chinese medicine; 5. The main causes of infertility are fallopian tube factors rather than hypothalamus and other endocrine diseases(hypothyroidism or hyperthyroidism, diabetes, etc.), polycystic ovary syndrome (PCOS), severe pelvic endometriosis, adenomyosis, etc.; 6. Patients agree to participate in this clinical study and sign an informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients with a history of steroid therapy and uterine cavity operation within 3 months; 2. Patients with clear and serious other organic diseases of reproductive organs; 3. With ovarian premature failure, previous ovarian surgery history and only single ovarian; 4. With PCOS, adenomyosis, uterine malformations, chromosomal abnormalities, ovarian tumors, and other endocrine diseases(diabetes, thyroid dysfunction, etc.); 5. With hereditary diseases that are not suitable for production, and are currently not capable of being diagnosed by preimplantation genetics under the Maternal and Child Health Act; 6. The couple merged with Severe primary diseases of the cardiovascular, hepatic, renal or hematopoietic systems , or with mental illness; 7. Either of the couple has serious addictions such as drug use and exposure to teratogenic rays, poisons, and drugs and is in the action period; 8. With allergic constitution and allergy to many drugs; 9. Can not insist on treatment.

Design outcomes

Primary

MeasureTime frame
Quality Embryonic Rate;

Countries

China

Contacts

Public ContactHong Yan

Tongji Hospital Affiliated to Tongji University

have_time_off@126.com+86 13917858864

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026