Multiple myeloma
Conditions
Interventions
Not grouped:Plasma-free replacement
Sponsors
Department of Hematology, Zhongnan Hospital, Wuhan University
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients with MM confirmed by bone marrow morphology and immunology; 2. Patients with a stable condition after routine treatment; 3.Patients with renal insufficiency or M protein abnormalities; 4.60-80 years old; 5.With liver and kidney function: blood bilirubin <= 35µmol / L, AST / ALT below 2 times the upper limit of normal value, blood creatinine <= 150µmol / L; 6. With normal heart function; 7. Physical condition score 0-2 (ECOG score); 8. Get informed consent from patient or family member.
Exclusion criteria
Exclusion criteria: 1. Patients with allergies or obvious contraindications to any drug involved in the program; 2. With severe heart disease, including myocardial infarction and cardiac insufficiency; 3.With malignant tumors of other organs; 4.With active phase of TB patients and HIV positive patients; 5.Patients with other blood system diseases at the same time; 6. Pregnant or lactating women; 7. Patients who do not understand or follow the protocol; 8. With previous history of intolerance or allergy to similar drugs; 9. Patients who are also participating in other clinical researchers; 10. Any other circumstances that hinder the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| M protein content in plasma; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood routine;Liver and kidney function;Patient complication rate;Assess patient symptoms;Neutrophil recovery time;Hemoglobin recovery time;Platelet recovery time; | — |
Countries
China
Contacts
Public ContactFuling Zhou
Department of Hematology, Zhongnan Hospital, Wuhan University
Outcome results
None listed