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Responsiveness of Pulmonary Artery-Related Severe Pulmonary Hypertension to PAH Targeting Drugs and Prognostic Risk Factors

Responsiveness of Pulmonary Artery-Related Severe Pulmonary Hypertension to PAH Targeting Drugs and Prognostic Risk Factors

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000030626
Enrollment
Unknown
Registered
2020-03-08
Start date
2020-03-03
Completion date
Unknown
Last updated
2020-03-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pulmonary hypertension

Interventions

PAH-targeted therapy and No PAH-targeted therapy:PAH-targeted therapy

Sponsors

The First Affiliated Hospital of Guangzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. All patients with pulmonary parenchymal lesions between the ages of 18 and 80 years, at sea level, were examined by right heart catheterization at rest mPAP >= 35mmHg or mPAP>= 25mmHg and CI the accompanying pulmonary artery Diameter; bronchus within l cm below the pleura; 5. Other lung diseases were diagnosed according to the criteria of the recent 3 years of diagnosis and treatment of each underlying disease.

Exclusion criteria

Exclusion criteria: 1. All with a history of allergic diseases such as bronchial asthma, severe OSAS lung cancer and tuberculosis; 2. Patients with wasting diseases such as acute and chronic liver, kidney, digestive system, malignant tumors, hyperthyroidism, etc .; 3. All patients with poor compliance, do not follow the doctor's advice, stop taking or take other traditional Chinese medicine, do not cooperate Treat patients; 4. All patients with connective tissue disease, physical disability and mental disorders.

Design outcomes

Primary

MeasureTime frame
NT-proBNP;NYHA functional class;Mean pulmonary artery pressure;Pulmonary vascular resistance;6 minutes walking distance;

Countries

China

Contacts

Public ContactHong Cheng

The First Affiliated Hospital of Guangzhou Medical University

gyfyyhc@126.com+86 13640815889

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026