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A study for the nutritional intervention of deep hydrolysis of whey protein in patients with postoperative hypoproteinemia after gastrectomy

A study for the nutritional intervention of deep hydrolysis of whey protein in patients with postoperative hypoproteinemia after gastrectomy

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000030601
Enrollment
Unknown
Registered
2020-03-08
Start date
2020-03-16
Completion date
Unknown
Last updated
2020-03-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypoproteinemia after gastric cancer

Interventions

experimental group A:Hydrolyzed whey protein 10g 3/d
experimental group B:Isolate whey proteins 10g 3/d
control group:regular diet instruction

Sponsors

Nutrition Department of the first medical center of PLA General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged from 18 to 70 years old, male or female, 1 week after surgery for gastric cancer; 2. Plasma albumin (ALB) 25-35g/L; 3. Hemoglobin (Hb)>90g/L; 4. BMI > 16 kg/m2; 5. There was no subjective weight loss of >5% in the recent 3 months, or no subjective weight loss of >10% in the recent 6 months; 6. Informed consent and signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients who received albumin infusion or used drugs that affect protein metabolism in the past month; 2. With severe secondary hyperparathyroidism, uremia, poor heart function, infection, cardiovascular calcification and other complications; 3. Combined with high catabolic state; 4. Patients with severe gastrointestinal dysfunction unable to tolerate oral nutrition supplement; 5. Patients with massive exudation of pleural effusion/ascites or massive urine protein; 6. Those who are allergic to any component of the product and any factors that the researcher considers inappropriate for the study; 7. Patients with poor compliance who do not cooperate with the investigator.

Design outcomes

Primary

MeasureTime frame
Serum albumin;prealbumin;immunoglobulin;

Secondary

MeasureTime frame
Dietary survey;Body composition analysis;Blood biochemical test;

Countries

China

Contacts

Public ContactLiu Yinghua

Chinese PLA General Hospital

liuyinghua77@163.com+86 10-66939619

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026